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The procedure is done under general anaesthetic , usually through keyhole surgery , and most patients stay in hospital for 1 to 3 days

Pregnancy and lactation are typically considered contraindications unless specifically approved by obstetric care

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Here, we demonstrate that dihexa binds with high affinity to hepatocyte growth factor (HGF) and both dihexa and its parent compound Norleucine 1-AngIV (Nle1- AngIV) induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF- dependent cell scattering