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Just as important is treating the epileptic pregnant patient, since this requires special knowledge of which AEDs pharmacokinetic profiles are affected by pregnancy, so dosage adjustment can be instituted to avoid breakthrough seizures
Therefore, at least to some extent, AS should be considered as an autoimmune disease (Shoenfeld et al., 2001
Concerning adverse outcomes, it is significant to note that 99.68% of patients experienced at least one serious adverse outcome, with 5.06% resulting in death (DE) and 15.27% classified as life-threatening (LT)
