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Cancer 94, 15931611

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1 Introduction Neurological diseases are multifactorial disorders caused by intrinsic and extrinsic factors, such as genetics, epigenetics, age and environmental factors, which result in cognitive dysfunction and behavioral disorders ( Epigenetic mechanisms, such as DNA methylation, non-coding RNA regulation, and histone modifications, are involved in these processes ( In the context of neural development, DNA methylation has emerged as a crucial mechanism in regulation of neural stem cell proliferation, synaptic plasticity, and neuronal repair ( 2 DNA methylation DNA methylation is catalyzed by DNA methyltransferases (DNMTs) with the transferring a methyl group to the cytosine ring within both CpG and non-CpG dinucleotides (32)

My role: I schedule collection of, processed, catalogued, and analyzed blood samples to quantify T/B/NK counts (Ficoll gradient and Flow cytometry), viral load (qPCR), anti-SIV IgG concentration (ELISA), and SIV specific T cell specificity (Flow cytometry & ELISPOT)