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Concomitantly, sulforaphane significantly reduced the nuclear translocation of the pro-inflammatory transcription factor nuclear factor (NF)-B in pancreatic acinar cells, downregulating the expression of NF-B target genes that code for pro-inflammatory mediators, such as tumor necrosis factor- (TNF-), interleukin-1 (IL-1), and IL-6 ( Figure 3 ) (18)

doi: 10.17219/acem/154955 27 ChoS

While FcgRI receptors are often bound by monomeric IgG, this does not inhibit their activation by IgG immune complexes
