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The clinical use of Dox is hindered by its dose-dependent cumulative cardiotoxicity caused by free radicals
Marsian, J
That is, EGT could couple GSH to reduce ferryl myoglobin, chelate transition metal iron to scavenge ROS/RNS and free radicals generated during IR, regulate proinflammatory cytokines like interleukin-1 (IL-1) and tumor necrosis factor- (TNF-), and ultimately prevent myocardial injury ( 2.2.2 Liver Diseases The damage of IR to the liver is also extremely significant
Jan 21 2020;9(2)doi:10.3390/jcm9020297 Ehrmann DA
