oral glutathione skin whitening randomized trial Effect of an Formulation on Lightening: Results from In Vitro Tyrosinase Inhibition to a Double-Blind Placebo-Controlled Clinical Study in Healthy Asian Participants Glutathione as a skin‐lightening agent
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this phenomenon generally occurs as a consequence from the activation of other receptors or signaling pathways
This involves complex, multi-modal mechanism where astrocytes listen to synaptic activity and respond through (a) glutamate uptake and recycling via the glutamate-glutamine cycle, (b) increased glycolysis and shuttling of metabolites to neurons for oxidative phosphorylation, and (c) elevated Ca 2+ signaling and release of vasoactive molecules for blood flow control
