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In a genetic mouse model, the loss of zinc transporter Zip10 leads to reduced zinc levels in macrophages, triggering p53-dependent apoptosis [74]
CRI measures the ability of light to reveal the colors of objects
Rylaze-BI4916 treatment in AML cell lines led to the inhibition of cap-dependent mRNA translation and protein synthesis, as well as a marked decrease in intracellular glutathione levels, a critical cellular antioxidant
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