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This buffer ratio varies with the pH, but owing to its relatively low concentration, it contributes little to the buffering capacity of the extracellular fluid

In this study, we engineer an AC4A-modified supramolecular albumin nanoparticle (SHC4H) to treat hypoxic tumors

Astrocytes 2.4

As a consequence, the invasion of gram negative enterobacteria initiate the inflammatory cascade wherein Toll like receptor-4 (TLR-4)-induced proinflammatory cytokine upsurge along with NLRP3 inflammosome activation attract the neutrophils eventually leading to oxidative burst, chronic inflammation, apoptosis and ultimately intestinal ulceration [140]