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Another important element in human GCL gene promoters that responds to electrophiles in cells and increases gene expression is the EpRE or electrophile response element (Rushmore et al., 1991

While individual responses can vary, most patients report visible improvements within 6-12 weeks of consistent treatment

Then, we make some classifications of GSH-responsive and -exhausting metal nanomedicines used in cancer therapy, including inorganic nanomaterials, metal-organic frameworks (MOFs), and platinum-based nanomaterials

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