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However, in other children, neither or only one of the two gene changes can be found, even though we know they are present

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Nevertheless, another in vitro study in rat vascular smooth muscle cells revealed that CRP increased mRNA levels and the protein expressions of VEGF-A and inducible nitric oxide synthase, and boosted NO secretion in the medium, but it also hindered the nuclear translocation of glucocorticoid receptor and diminished its mRNA level and protein phosphorylation in these cells [142]