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In vivo trinitrobenzenesulfonic acid-induced colitis rats were treated with desmethylbellidifolin from G
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Upon activation, Nrf2 translocates to the nucleus, binds to antioxidant response elements (AREs) in DNA, and induces the expression of cytoprotective genes such as heme oxygenase-1 (HO-1), NAD(P)H quinone dehydrogenase 1 (NQO1), and -glutamylcysteine ligase catalytic subunit (-GCLC) [2,3,26]
