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Bai YR, Yang WG, Hou XH, et al
doi: 10.1016/j.isci.2023.106359
Furthermore, FXR transcriptionally activates Acsl4 in intestinal epithelial cells (IECs), promoting ferroptosis and subsequently impairing ILC3 function, and can induce Wnt2b in cancer-associated fibroblasts (CAFs) within the tumor stroma, fostering a pro-tumorigenic niche (92, 93)
