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Plant and animal GSTs play a key role in conjugating GSH with such endogenously produced electrophiles, which results in their detoxification (Bartling et al., 1993
"Treatment of human peripheral lymphocytes with concanavalin A activates expression of glutathione reductase"

Among these are IGF-I and TSH, both of which are critical to thyroid hormone synthesis ( Figure 3 )

Morris, A
