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The two cysteines in this motif catalyze glutathione (GSH)-dependent thiol-disulfide exchange reactions, i.e., the reduction of protein disulfides and, with high specificity, reversible (de-)glutathionylation [19] Oxidized Grxs are reduced by GSH, the resulting GSH disulfide (GSSG) by glutathione reductase (GR) using NADPH as electron source [20]

Inhibition of fatty acid metabolism by etomoxir or TOFA suppresses murine dendritic cell activation without affecting viability

Worth knowing: research-chemical territory, and for most people the dominant effect is hunger rather than muscle

Direct administration of BHB is associated with decreased proteinuria, reduced renal hypertrophy, and improved histological features in mice with streptozotocin-induced DM [104]