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Kurano M, Okamoto K, Jubishi D, Hashimoto H, Sakai E, Saigusa D, Kano K, Aoki J, Harada S, Okugawa S, et al

In conclusion, our study focused on unravelling the regulation of the GABAergic pathway in SMA, providing new evidence supporting the involvement of the cortical motor network in exacerbating disease progression through E/I imbalance, while also linking SMA to other neurodegenerative movement disorders

In mice lacking liver-specific IR, the nuclear active form of SREBP2 protein is drastically reduced in all feeding conditions, highlighting the dependency on insulin signaling for protein activation (221)