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The supernatant was then collected and diluted 1:5 with the assay buffer by mixing 1 part supernatant with 4 parts assay buffer, resulting in a final SSA concentration of 1%
Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo
In Nkolbisson, the CYP6AA7 and CYP6Z10 genes were overexpressed 7.46- and 4.32- times, respectively, along with both Esterase genes (21.3-folds for Esterase A and 15.4-folds for Esterase B ) (Fig
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