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Mitochondrial dysfunction, as induced by neurotoxicants, such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and rotenone, augments oxidative stress in nigral neurons [16, 28]

Int Immunopharmacol 72:445453 Lin X et al (2020) Ameliorate effect of Pyrroloquinoline quinone against cyclophosphamide-induced nephrotoxicity by activating the Nrf2 pathway and inhibiting the NLRP3 pathway
In addition, Arabidopsis seedlings exposed to 55 C heat stress have been used as a model for ferroptotic-like cell death in plants (Distefano et al., 2017)

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