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These systems may uniquely enable the study of patient-specific immuneCNS interactions, remyelination failure mechanisms and candidate neuroprotective or myelin-promoting therapies under inflammatory conditions that better mirror the progressive form of neuroinflammatory demyelination

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Weight loss : Retatrutide showed 28.7% at 68 weeks (Phase 3 TRIUMPH-4) versus CagriSema's 20.4% at 68 weeks (Phase 3 REDEFINE 1), though cross-trial comparisons are limited

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