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Amphetamine increases the concentration of dopamine in the synaptic cleft by entering the presynaptic neuron by diffusing across the neuronal membrane directly or through DAT, competitive reuptake inhibition at the transporter, and finally, the reversal of dopamine transport through DAT (i.e., dopamine efflux) [159,160,161]

Some studies showed that a series of 3 injections a few weeks apart achieved better results when compared to a single injection, which can be considered for maximum effect

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